Whilst digging a new UnderGround line in London, the construction crew employed for the job discover the skeletal remains of ancient apes with extraordinarily large skulls, shortly after that they unearth what appears to be an old World War II German missle.
However when a Missile expert, called Colonel Breen (Julian Glover) is brought in to investigate, accompanied by Professor Bernard Quartermass (Andrew Keir) it transpires that, not only is it NOTa German missile, but that it is not of this world either.
When the interior of the artefact is exposed, a dead locust-like creature that resembles the devil is found. It is soon determined by Quartermass that these "locusts" are evil Martians who altered the brains of our simian ancestors to eventually lay claim to the Earth.
When Quartermass's suspicion that the missile can reactivate the dormant evil in humans is confirmed, all hell breaks loose.