The story behind this film follows the lives of two very dear friends. The friends are; Father Brian Kilkenney Finn (Edward Norton) who is a Catholic priest, and Rabbi Jacob Schram (Ben Stiller).
Their friendship has endured a lot in the time they have know each other, they have been their for each other through lots of things, however what is about to happen will test their friendship and loyalty to their seperate callings in life to the limit.
When the two meet Anna Riley (Jenna Elfman) things start top go awry as the two both fall passionately in love with the girl.
However, neither of them are at liberty to pursue any kind of relationship with her due to their religious beleifs and what is expected of them due to their positions. Brian can't enter the relationship due to his vow of celebacy, and Rabbi Jake can't because she isn't Jewish.