Boys and Girls (2000)

Ryan Williams (Freddy Prinze Jr.) and Jennifer Burrows (Claire Forlani) don't get along at all when they first meet each other as children.

Eventually, however, the two become very good friends, then later take a shot at a romance.

This is the story which follows their quirky relationship from childhood to young adulthood.

Often reported to be a "When Harry Met Sally" for teenagers.