The film that does what it says on the tin. Samuel L. Jackson plays Neville Flynn, an FBI agent escorting Sean Jones, a witness to a gangland slaying, from Hawaii to Los Angeles.
However, the gangster, Eddie Kim, has secreted crates of venomous serpents in the cargo hold and when they're released, all hell breaks lose. The film earned a reputation for the inclusion of plot lines from blogging fans, including one now infamous line.
Despite the novel approach to its production, David R Ellis's film is surprisingly well-acted and tense, with both Julianna Margulies as flight attendant Claire Miller and David Koechner as co-pilot Rick receiving a share of the cracking dialogue.